Challenges in radiological evaluation of brain metastases, beyond progression

Radiologia (Engl Ed). 2024 Mar-Apr;66(2):166-180. doi: 10.1016/j.rxeng.2024.03.003. Epub 2024 Mar 25.ABSTRACTMRI is the cornerstone in the evaluation of brain metastases. The clinical challenges lie in discriminating metastases from mimickers such as infections or primary tumors and in evaluating the response to treatment. The latter sometimes leads to growth, which must be framed as pseudo-progression or radionecrosis, both inflammatory phenomena attributable to treatment, or be considered as recurrence. To meet these needs, imaging techniques are the subject of constant research. However, an exponential growth after radiotherapy must be interpreted with caution, even in the presence of results suspicious of tumor progression by advanced techniques, because it may be due to inflammatory changes. The aim of this paper is to familiarize the reader with inflammatory phenomena of brain metastases treated with radiotherapy and to describe two related radiological signs: "the inflammatory cloud" and "incomplete ring enhancement", in order to adopt a conservative management with close follow-up.PMID:38614532 | DOI:10.1016/j.rxeng.2024.03.003
Source: Radiologia - Category: Radiology Authors: Source Type: research