miR-30a-5p mediates ferroptosis of hippocampal neurons in chronic cerebral hypoperfusion-induced cognitive dysfunction by modulating the SIRT1/NRF2 pathway

CONCLUSION: miR-30a-5p induces hippocampal neuronal ferroptosis and exacerbates post-CCH cognitive dysfunction by targeting SIRT1 and reducing NRF2 nuclear translocation.PMID:38636610 | DOI:10.1016/j.brainresbull.2024.110953

Source: Brain Research - April 18, 2024 Category: Neurology Authors: Lihua Wang Mingjie Li Bing Liu Ruihan Zheng Xinyi Zhang Shuoyi Yu Source Type: research