Genetic underpinnings of fasting and oral glucose-stimulated based insulin sensitivity indices

CONCLUSION: Even though the IS indices mostly share a common genetic background, notable differences emerged between OGTT0,120 indices. The fasting and OGTT based indices have distinct associations with T2D risk variants. This work provides a basis for future large-scale genetic investigations into the differences between IS indices.PMID:38635292 | DOI:10.1210/clinem/dgae275
Source: The Journal of Clinical Endocrinology and Metabolism - Category: Endocrinology Authors: Source Type: research