Long-Term Outcomes of Bioprosthetic Valves in the Mitral Position: A Pooled Meta-Analysis of Reconstructed Time-to-Event Individual Patient Data

Bioprosthetic mitral valve replacement (bMVR) use is increasing; however, data regarding long-term durability are lacking. We sought to perform a reconstructed individual patient data meta-analysis from published Kaplan –Meier curves to ascertain survival, freedom from valve degeneration, and reoperation in studies published since 2010. We explored the effects of age and valve type (bovine pericardial or porcine valve) on outcomes. We searched MEDLINE, OVID, Embase, and Cochrane CENTRAL for studies reporting at l east 3 years of follow-up after bMVR and published since 2010.

Source: The American Journal of Cardiology - April 16, 2024 Category: Cardiology Authors: Marinos Koulouroudias, Michele Di Mauro, Giovanni Chiariello, Paolo Meani, Roberto Lorusso Source Type: research