How much of the outcome improvement after successful recanalization is explained by follow-up infarct volume reduction?

Conclusion 56% (95% CI 38% to 78%) of outcome improvement after successful recanalization was explained by FIV reduction. Results corroborate pathophysiological assumptions and confirm the value of FIV as an imaging endpoint in clinical trials. 44% (95% CI 22% to 62%) of the improvement in outcome was not explained by FIV reduction and reflects the remaining mismatch between radiological and clinical outcome measures.

http://jnis.bmj.com/cgi/content/short/16/5/459?rss=1

Source: Journal of NeuroInterventional Surgery - April 23, 2024 Category: Neurosurgery Authors: Kniep, H., Meyer, L., Broocks, G., Bechstein, M., Austein, F., McDonough, R. V., Brekenfeld, C., Flottmann, F., Deb-Chatterji, M., Alegiani, A., Hanning, U., Thomalla, G., Fiehler, J., Gellissen, S. Tags: Ischemic stroke Source Type: research