Benzo[a]pyrene exposure causes exonal switch resulting in reduced surface CD5 expression in an AHR-dependent manner

This study indicates that the polycyclic aromatic hydrocarbon decreases the sCD5 expression by upregulating alternative exon expression, which may adversely affect the overall T cell functions.PMID:38631465 | DOI:10.1016/j.imlet.2024.106858

Source: Immunology Letters - April 17, 2024 Category: Allergy & Immunology Authors: Smita Kumari Bharat Singh Amit Kumar Kureel Sheetal Saini Satya Prakash Aditi Chauhan Prabin Kumar Kulwant Singh Ambak Kumar Rai Source Type: research