GSE210983 AAV9-medated cardiac expression of lncRNA CARDINAL ameliorate TAC induced hypertrophy

Contributors : Yao W Lu ; Xin He ; Da-Zhi WangSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusPathological cardiac hypertrophy is featured by enhanced protein synthesis. Translation inhibition is effective in treating cardiac hypertrophy, yet with systematic side effect. We identified a cardiac-enriched LncRNA CARDINAL, when over-expressed in cardiomyocyte using AAV9 driven by cTNT promoter, ameliorate transaortic constriction (TAC) induced hypertrophy.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research
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