Effect of asiaticoside on systolic blood pressure and relaxation of isolated thoracic aorta of rats

CONCLUSION: Asiaticoside induces thoracic aorta relaxation by mediating high-conductance calcium-activated potassium channel opening, promoting nitric oxide release from endothelial cells and regulating Ca2+ influx and outflow, thereby reducing systolic blood pressure in rats.PMID:38597444 | PMC:PMC11006695 | DOI:10.12122/j.issn.1673-4254.2024.03.14

Source: Journal of Southern Medical University - April 10, 2024 Category: Universities & Medical Training Authors: G Lu H Sun Z Sun L Liu L Wang N Zhang Y Wang Y He J Ji X Li P Kang B Tang Source Type: research