Platelet function testing: update on determinant variables and permissive windows using a platelet-count-based device

While there are various aspects of platelet biology that can be studied in the lab (i.e. adhesion, degranulation, integrin activation), the master test for platelet function is that which gives a measure of the platelet aggregation capacity upon stimulation with an agonist. Platelet function testing is necessary for the diagnosis of platelet disorders and the monitoring of patients receiving anti-platelet treatments. Furthermore, it becomes relevant in the quality control of platelet concentrates for transfusion purposes, especially considering the global concern about long term storage, other forms of storage (i.e.

Source: Transfusion and Apheresis Science - April 17, 2024 Category: Hematology Authors: Patricia Villar, Sof ía Carreño, Sara Moro, Inés Díez Galindo, Ángel Bernardo, Laura Gutiérrez Source Type: research