Longitudinal evaluation of the cutaneous and rectal microbiota of German shepherd dogs with perianal fistulas undergoing therapy with ciclosporin and ketoconazole

CONCLUSIONS AND CLINICAL RELEVANCE: Changes in lesional cutaneous and rectal microbiota occur in German shepherd dogs with perianal fistulas and shift over time with lesion resolution during immunomodulatory therapy. Further investigations of the role of cutaneous and enteric microbiota in the pathogenesis of perianal fistulas, and whether manipulation of microbial populations may ameliorate disease, are needed.PMID:38616572 | DOI:10.1111/vde.13249

Source: Veterinary Dermatology - April 15, 2024 Category: Veterinary Research Authors: Christine L Cain Ellen White Lindsey E Citron Qi Zheng Daniel O Morris Elizabeth A Grice Charles W Bradley Source Type: research