Powerful and accurate detection of temporal gene expression patterns from multi-sample multi-stage single-cell transcriptomics data with TDEseq

We present a non-parametric statistical method called TDEseq that takes full advantage of smoothing splines basis functions to account for the dependence of multiple time points in scRNA-seq studies, and uses ...

Source: Genome Biology - April 15, 2024 Category: Genetics & Stem Cells Authors: Yue Fan, Lei Li and Shiquan Sun Tags: Method Source Type: research