A Real-world Toxicity Atlas Shows that Adverse Events of Combination Therapies Commonly Result in Additive Interactions

CONCLUSIONS: Our study provides a framework for analyzing adverse events and suggests that adverse drug interactions commonly result in additive effects with a high level of overlap of adverse event patterns. These real-world insights may advance the implementation of new combination therapies in clinical practice.PMID:38597991 | PMC:PMC11016889 | DOI:10.1158/1078-0432.CCR-23-0914

Source: Clinical Cancer Research - April 10, 2024 Category: Cancer & Oncology Authors: Asli K üçükosmanoglu Silvia Scoarta Megan Houweling Nicoleta Spinu Thomas Wijnands Niek Geerdink Carolien Meskers Georgi K Kanev Bert Kiewiet Mathilde Kouwenhoven David Noske Tom Wurdinger Marianne Pouwer Mark Wolff Bart A Westerman Source Type: research