Consolidating data on the association of IL-6 and IL-10 polymorphisms with the development of glaucoma: a meta-analysis

CONCLUSIONS: The study found that IL-10 -592C>A, -819T>C, -1082A>G, and IL-6 -572 G>C polymorphisms were linked to glaucoma risk. However, no significant association was observed for IL-6 -174 G>C. These findings imply a possible connection between genetic variations in these genes and glaucoma risk. Further research is crucial to fully understand the underlying mechanisms and their significance in managing and preventing glaucoma.PMID:38602069 | DOI:10.1080/13816810.2024.2336964

Source: Ophthalmic Genetics - April 11, 2024 Category: Opthalmology Authors: Ahmadreza Golshan-Tafti Mohammad Bahrami Reyhaneh Mohsenzadeh-Yazdi Seyed Alireza Dastgheib Maryam Aghasipour Amirmasoud Shiri Kamran Alijanpour Fatemeh Asadian Kazem Aghili Mohammad Manzourolhojeh Hossein Neamatzadeh Source Type: research