Quinoxaline derivatives: Recent discoveries and development strategies towards anticancer agents

Eur J Med Chem. 2024 Apr 7;271:116360. doi: 10.1016/j.ejmech.2024.116360. Online ahead of print.ABSTRACTCancer is a leading cause of death and a major health problem worldwide. While many effective anticancer agents are available, most drugs currently on the market are not specific, raising issues like the common side effects of chemotherapy. However, recent research hold promises for the development of more efficient and safer anticancer drugs. Quinoxaline and its derivatives are becoming recognized as a novel class of chemotherapeutic agents with activity against different tumors. The present review compiles and discusses studies concerning the therapeutic potential of the anticancer activity of quinoxaline derivatives, covering articles published between January 2018 and January 2023.PMID:38614060 | DOI:10.1016/j.ejmech.2024.116360
Source: European Journal of Medicinal Chemistry - Category: Chemistry Authors: Source Type: research