Interstitial Pneumonia Associated with Nodal T-follicular Helper Cell Lymphoma: A Case Report

Intern Med. 2024 Apr 9. doi: 10.2169/internalmedicine.3601-24. Online ahead of print.ABSTRACTNodal T-follicular helper cell lymphoma (nTFHL), a hematologic neoplasm originating from T-follicular helper (TFH) cells, occasionally presents with pulmonary radiographic abnormalities, without neoplastic cellular infiltration. However, the precise mechanisms underlying non-neoplastic pulmonary opacities in patients with nTFHL remain unclear. Previous reports have shown that TFH cell abnormalities are associated with collagen disease and interstitial pneumonia with autoimmune features (IPAF). We herein report a patient with nTFHL accompanied by interstitial pneumonia diagnosed via lung and lymph node biopsies. These findings suggest the need to rule out nTFHL before diagnosing IPAF.PMID:38599858 | DOI:10.2169/internalmedicine.3601-24
Source: Internal Medicine - Category: Internal Medicine Authors: Source Type: research