Challenges encountered in predicting live birth after in  vitro fertilization in the different phenotypes of patients with polycystic ovary syndrome

Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility and endocrinopathy among women of reproductive age, with a reported prevalence of 10% –13% (1). Polycystic ovary syndrome is diagnosed using the latest international evidence–based guideline criteria (1, 2), necessitating the presence of two out of the following: clinical or biochemical hyperandrogenism; ovulatory dysfunction; and polycystic ovaries on ultrasound or specific anti müllerian hormone (AMH) levels. This approach has identified at least four distinct phenotypes: phenotype A-androgen excess + ovulatory dysfunction + polycystic ovary morphology; phenotype B-androgen excess + ovulatory dysfunction; phenotype C-androgen excess + polycystic ovary morphology; and phen otype D-ovulatory dysfunction + polycystic ovary morphology (1, 2).
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Reflections Source Type: research