Genetically predicted hypotaurine levels mediate the relationship between immune cells and intracerebral hemorrhage

In this study, our objective was to investigate the connections between immune cell characteristics and plasma metabolites, as well as the links between plasma components and ICH. Our investigation uncovered that the levels of hypotaurine play a key role in the advancement of ICH, influencing the ratio of switched memory B cells among lymphocytes. Thus, our findings provide novel insights into the potential biological mechanisms underlying immune cell-mediated ICH.PMID:38608476 | DOI:10.1016/j.intimp.2024.112049
Source: International Immunopharmacology - Category: Allergy & Immunology Authors: Source Type: research