Constitutive hypercoagulability in pediatric sickle cell disease patients with hemoglobin SS genotype

CONCLUSION: Our results indicate that pediatric SCD patients with the HbSS genotype have constitutively activated hemostasis relative to HbSC patients and healthy children. It remains to be determined how treatments that improve clinical outcomes in SCD patients affect this constitutively hypercoagulable state.PMID:38605827 | PMC:PMC11004888 | DOI:10.1016/j.rpth.2024.102374

Source: Cell Research - April 12, 2024 Category: Cytology Authors: Raizl G Sussman Joy Mburu MacGregor Steele Annie Bang Jeremy Friedman Ran Goldman Melanie Kirby Margaret L Rand Victor S Blanchette Fred G Pluthero Suzan Williams Walter H A Kahr Source Type: research