Acute Rejection Rates in Vascularized Composite Allografts: A Systematic Review of Case Reports

CONCLUSIONS: In contrast to previous statements, the field of VCA is not rapidly evolving, as it has encountered challenges in addressing immune-related concerns. This is highlighted by the absence of a standardized immunosuppression regimen. Consequently, more substantial data are required to draw more conclusive results regarding the immunogenicity of VCAs and the potential superiority of one immunosuppressive treatment over another. Future efforts should be made to report the VCA surgeries comprehensively, and muti-institutional long-term prospective follow-up studies should be performed to compare the number of acute rejections with influencing factors.PMID:38603944 | DOI:10.1016/j.jss.2024.02.019

Source: Hand Surgery - April 11, 2024 Category: Surgery Authors: Lo ïc Van Dieren Pierre Tawa Marie Coppens Laura Naenen Omer Dogan Tom Quisenaerts Hyshem H Lancia Ha ïzam Oubari Yohann Dabi Maxime De Fr é Filip Thiessen Ef Curtis L Cetrulo Alexandre G Lellouch Source Type: research