Comparison of the efficacy of propranolol versus amitriptyline as monotherapy for prophylaxis of migraine

CONCLUSION: The average number of migraine attacks reduced in the amitriptyline and propranolol groups as the treatment duration increased. Amitriptyline is a popular medication with established effectiveness and manageable levels of negative side effects. It is the tricyclic antidepressant that is most frequently used to prevent headaches. When administered for migraine prevention, it generates a quick response within 3 months. Propranolol is less effective than amitriptyline at reducing the frequency, length, and severity of episodes.PMID:38605779 | PMC:PMC11006045 | DOI:10.4103/jfmpc.jfmpc_927_23

Source: Primary Care - April 12, 2024 Category: Primary Care Authors: Krinaben M Patel Kachhadia M Popatbhai Roshni Xavier Mohammed A S Aramin Khalid J F Faris Mohammed A Mateen Priyadarshi Prajwal Mohammed D M Marsool Hafsa Sheikh Esra H A G Mohamed Source Type: research