Serum biomarker levels predict disability progression in patients with primary progressive multiple sclerosis

Conclusions Levels of sNfL, sGFAP and sCHI3L1 are prognostic biomarkers associated with disability progression in patients with PPMS, being CHI3L1 findings less dependent on the inflammatory component associated with disease progression.

http://jnnp.bmj.com/cgi/content/short/95/5/410?rss=1

Source: Journal of Neurology, Neurosurgery and Psychiatry - April 12, 2024 Category: Neurosurgery Authors: Fissolo, N., Benkert, P., Sastre-Garriga, J., Mongay-Ochoa, N., Vilaseca-Jolonch, A., Llufriu, S., Blanco, Y., Hegen, H., Berek, K., Perez-Miralles, F., Rejdak, K., Villar, L. M., Monreal, E., Alvarez-Lafuente, R., Soylu, O. K., Abdelhak, A., Bachhuber, F Tags: Multiple sclerosis Source Type: research