Inadequacies in Reporting and Representation of Sex and Gender in Randomized Clinical Trials of Chronic Pain Interventions: An ACTTION COPASETIQ Review

The concepts of sex and gender are often incorrectly used in health research. Sex is a biological construct while gender is a social construct, but both may have differential effects on the outcome of pain treatments. To better understand how chronic pain trials collect, report, and analyze data regarding sex and gender we conducted a targeted systematic review of randomized clinical trials of pharmacological and non-pharmacological treatments for various chronic pain conditions. Across 6 pain specialty journals, 2,883 abstracts from papers published 2016-2021 were screened, and 73 manuscripts ultimately reviewed for reporting and analysis of sex and gender.
Source: The Journal of Pain - Category: Materials Science Authors: Source Type: research