Small extracellular vesicles facilitate epithelial-mesenchymal transition in chronic rhinosinusitis with nasal polyps via the miR-375-3p/QKI axis

CONCLUSIONS: MiR-375-3p-enriched sEVs facilitated EMT by suppressing QKI in hNECs. The association of miR-375-3p with disease severity underscores its potential as both a diagnostic marker and a therapeutic target for the innovative management of CRSwNP.PMID:38557580 | DOI:10.4193/Rhin23.520

Source: Rhinology - April 1, 2024 Category: ENT & OMF Authors: X Wang R Zheng W Liang H Qiu T Yuan W Wang H Deng W Kong J Chen Y Bai Y Li Y Chen Q Wu S Wu X Huang Z Shi Q Fu Y Zhang Q Yang Source Type: research