Identification of idiopathic pulmonary fibrosis hub genes and exploration of the mechanisms of action of Jinshui Huanxian formula

In conclusion, a series of IPF hub genes was identified, and validated in an independent dataset, mice with PF, and MRC-5 cells. Moreover, the abnormal gene expression was normalized by JHF. These findings provide guidance for further exploration of the pathogenesis and treatment of IPF.PMID:38593509 | DOI:10.1016/j.intimp.2024.112048

Source: International Immunopharmacology - April 9, 2024 Category: Allergy & Immunology Authors: Qingzhou Guan Zhenzhen Zhang Peng Zhao Lidong Huang Ruilong Lu Chunlei Liu Yakun Zhao Xuejie Shao Yange Tian Jiansheng Li Source Type: research