Pulchinenoside B4 ameliorates oral ulcers in rats by modulating gut microbiota and metabolites

This study demonstrated that the gut microbiota and metabolites were altered in the OU rat model, which were significantly restored to the normal level by B4, thereby showing good application prospects in the treatment of OU. KEY POINTS: • The first investigating the correlation between OU and gut microbiota. • A close correlation between metabolites and gut microbiota in OU disease was successfully identified. • Pulchinenoside B4 ameliorates oral ulcers in rats by modulating gut microbiota and metabolites.PMID:38592514 | DOI:10.1007/s00253-024-13099-1

Source: Applied Microbiology and Biotechnology - April 9, 2024 Category: Microbiology Authors: Dewei Luo Li Yan Zhujun Wang Xiaofan Ji Na Pei Jing Jia Yingying Luo Hui Ouyang Shilin Yang Yulin Feng Source Type: research