Computational and experimental identification of keystone interactions in Ebola virus matrix protein VP40 dimer formation

This study sheds light on the structural origins of VP40 dimer formation and may inform the design of a small molecule that can disrupt VP40 dimer stability.

Source: Protein Science - April 9, 2024 Category: Biochemistry Authors: Yogesh Narkhede, Roopashi Saxena, Tej Sharma, Jacob P. Conarty, Valentina Toro Ramirez, Balindile B. Motsa, Souad Amiar, Sheng Li, Prem P. Chapagain, Olaf Wiest, Robert V. Stahelin Tags: RESEARCH ARTICLE Source Type: research