Proactive Diagnosis and Tailor-Made Treatment of Patent Ductus Arteriosus in Very Preterm Infants with Routine Echocardiography in Japan: A post hoc Analysis of the PLASE Study

CONCLUSIONS: The clinical management of PDA in Japan featured (1) COX-I administration based on echocardiographic findings before symptomatic or hemodynamically significant PDA appeared and (2) frequent discontinuation of therapeutic COX-I before completing the standard three doses course.PMID:38593757 | DOI:10.1159/000538363

Source: Neonatology - April 9, 2024 Category: Perinatology & Neonatology Authors: Seiichi Tomotaki Tetsuya Isayama Tohru Kobayashi Satoshi Masutani Hidenori Kawasaki Atsushi Nakayama Toshifumi Ikeda Katsuaki Toyoshima PLASE Study Group Investigators Source Type: research