STING inhibition suppresses microglia-mediated synapses engulfment and alleviates motor functional deficits after stroke

Ischemic stroke is the leading cause of adult disability. Ischemia leads to progressive neuronal death and synapse loss. The engulfment of stressed synapses by microglia further contributes to the disruption o...

Source: Journal of Neuroinflammation - April 8, 2024 Category: Neurology Authors: Chaoran Wu, Shiwen Zhang, Hao Sun, Ao Li, Fengsheng Hou, Long Qi and Hong Liao Tags: Research Source Type: research