Topical Versus Intravenous Tranexamic Acid in Patients Undergoing Cardiac Surgery: The DEPOSITION Randomized Controlled Trial

CONCLUSIONS: Among patients having cardiac surgery, topical administration of tranexamic acid resulted in an 8.3% absolute increase in transfusion without reducing the incidence of seizure, compared to intravenous tranexamic acid.PMID:38587333 | DOI:10.1161/CIRCULATIONAHA.124.069606

Source: Atherosclerosis - April 8, 2024 Category: Cardiology Authors: Andr é Lamy Dmitry A Sirota Frederic Jacques Ahmad Poostizadeh Nicolas Noiseux Sergey Efremov Philippe Demers Boris Akselrod Chew Yin Wang Rakesh C Arora Piotr Branny Shay P McGuinness Craig D Brown Hugues Jeanmart Qiang Zhao Haibo Zhang Emilie P Belley- Source Type: research