The Impact of Pre-Stroke Metformin Use on Clinical Outcomes after Acute Ischemic Stroke: A Systematic Review and Meta-Analysis

Stroke stands as one of the most devastating medical conditions and societal burdens, ranking as the third-leading cause of both death and disability on a global scale1. Diabetes mellitus, specifically type 2 diabetes mellitus (T2DM), is not just a prevalent medical condition but also a known risk factor for stroke, contributing to both its occurrence and recurrence2-5. The complexities tied to diabetes make it a focal point of investigation, especially given that hyperglycemia upon admission has been correlated with unfavorable outcomes post-stroke2, 6-8.

Source: Journal of Stroke and Cerebrovascular Diseases - April 9, 2024 Category: Neurology Authors: Madona Pakkam, Atakan Orscelik, Basel Musmar, Hatem Tolba, Sherief Ghozy, Yigit Can Senol, Cem Bilgin, Sandeep Samethadka Nayak, Ramanathan Kadirvel, Waleed Brinjikji, Alejandro A Rabinstein, David F Kallmes Source Type: research