Modulating the phenotype and function of bone marrow-derived macrophages via mandible and femur osteoblasts

In conclusion, our investigation showed that MOBs and FOBs have the ability to modulate MØ phenotype and function, with MOBs exhibiting a stronger regulatory potential. These findings provide a new direction for improving therapeutic strategies for bone regeneration in autologous bone grafts from the perspective of the immune microenvironment.PMID:38583238 | DOI:10.1016/j.intimp.2024.112000

Source: International Immunopharmacology - April 7, 2024 Category: Allergy & Immunology Authors: Li Li Yijuan Liu Xueshen Qian Ling Zhou Yujie Fan Xue Yang Kai Luo Yuling Chen Source Type: research