Viruses, Vol. 16, Pages 575: The High Capacity of Brazilian Aedes aegypti Populations to Transmit a Locally Circulating Lineage of Chikungunya Virus

Viruses, Vol. 16, Pages 575: The High Capacity of Brazilian Aedes aegypti Populations to Transmit a Locally Circulating Lineage of Chikungunya Virus Viruses doi: 10.3390/v16040575 Authors: Amanda de Freitas Fernanda Rezende Silvana de Mendonça Lívia Baldon Emanuel Silva Flávia Ferreira João Almeida Siad Amadou Bruno Marçal Sara Comini Marcele Rocha Hegger Fritsch Ellen Santos Thiago Leite Marta Giovanetti Luiz Carlos Junior Alcantara Luciano Moreira Alvaro Ferreira The incidence of chikungunya has dramatically surged worldwide in recent decades, imposing an expanding burden on public health. In recent years, South America, particularly Brazil, has experienced outbreaks that have ravaged populations following the rapid dissemination of the chikungunya virus (CHIKV), which was first detected in 2014. The primary vector for CHIKV transmission is the urban mosquito species Aedes aegypti, which is highly prevalent throughout Brazil. However, the impact of the locally circulating CHIKV genotypes and specific combinations of local mosquito populations on vector competence remains unexplored. Here, we experimentally analyzed and compared the infectivity and transmissibility of the CHIKV-ECSA lineage recently isolated in Brazil among four Ae. aegypti populations collected from different regions of the country. When exposed to CHIKV-infected AG129 mice for blood feeding, all the mosquito populations displayed high infection rates and disse...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research