NFKBIZ regulates NF κB signaling pathway to mediate tumorigenesis and metastasis of hepatocellular carcinoma by direct interaction with TRIM16

In conclusion, our study demonstrated that NFKBIZ regulated HCC tumorigenesis and metastasis by mediating NFκB signal transduction and TRIM16/NFKBIZ/NFκB axis may be the underlying mechanism of sorafenib insensitivity in HCC.PMID:38581570 | DOI:10.1007/s00018-024-05182-7
Source: Cellular and Molecular Life Sciences : CMLS - Category: Cytology Authors: Source Type: research