Discovery of a novel small-molecule activator of SIRT3 that inhibits cell proliferation and migration by apoptosis and autophagy-dependent cell death pathways in colorectal cancer

In conclusion, these findings demonstrate that the novel small-molecule activator of SIRT3 may hold a therapeutic potential as a drug candidate in colorectal cancer.PMID:38579616 | DOI:10.1016/j.bioorg.2024.107327

Source: Bioorganic Chemistry - April 5, 2024 Category: Chemistry Authors: Yi Mou Yanmei Chen Zhichao Fan Liansong Ye Bing Hu Bo Han Guan Wang Source Type: research