Lactobacillus plantarum 45 activates SHP2 through inhibition of oxidative stress to regulate osteoblast and osteoclast differentiation

CONCLUSION: LP45 can exert its antioxidant effect by inhibiting the production of oxidative stress to activate the SHP2 signaling pathway, thus promoting osteoblast differentiation and repressing osteoclast formation to maintain bone homeostasis and improve bone metabolism.PMID:38575308 | DOI:10.18632/aging.205708

Source: Aging - April 4, 2024 Category: Biomedical Science Authors: Yaming Yang Zheng Yan Qi Xie Yong Wang Zhiying Liu Min Lei Source Type: research