Proteomics Impact on Cell Biology to Resolve Cell Structure and Function

Mol Cell Proteomics. 2024 Apr 2:100758. doi: 10.1016/j.mcpro.2024.100758. Online ahead of print.ABSTRACTThe acceleration of advances in proteomics has enabled integration with imaging at the EM and LM levels, cryo-electron microscopy of protein structures, and artificial intelligence (AI) with proteins comprehensively and accurately resolved for cell structures at nm to sub-nm resolution. Proteomics continues to outpace experimentally based structural imaging, but their ultimate integration is a path towards the goal of a compendium of all proteins to understand mechanistically cell structure and function.PMID:38574860 | DOI:10.1016/j.mcpro.2024.100758
Source: Molecular and Cellular Proteomics : MCP - Category: Molecular Biology Authors: Source Type: research