Recovery from prolonged deep rocuronium-induced neuromuscular blockade : A randomized comparison of sugammadex reversal with spontaneous recovery.

CONCLUSIONS: This study confirms a prolonged residual blockade in patients who did not receive sugammadex, with median time to recovery > 1.5 h in the placebo group and one patient taking 4.8 h to achieve a safe level of neuromuscular function recovery following deep NMB. In contrast, sugammadex provided complete and reliable recovery of neuromuscular function (median time to recovery of 2.0 min). Thus, deep NMB with rocuronium until the end of the operation may be possible in combination with sugammadex reversal.
PMID: 26126940 [PubMed - as supplied by publisher]

Source: Der Anaesthesist - July 1, 2015 Category: Anesthesiology Authors: Rahe-Meyer N, Berger C, Wittmann M, Solomon C, Abels EA, Rietbergen H, Reuter DA Tags: Anaesthesist Source Type: research