Reirradiation for recurrent gynecologic cancer using high-dose-rate brachytherapy in Japan: A multicenter survey on practice patterns and outcomes

Radiotherapy (RT) plays an essential role in treatment of gynecological cancers, including cervical, endometrial, vulvar and vaginal cancers, and development of RT modalities, including chemoradiotherapy (CRT) and three-dimensional image-guided brachytherapy (3D-IGBT), has led to improved outcomes [1,2]. However, recurrence of gynecological cancer within the RT field remains as a significant clinical challenge. Even in well-controlled prospective clinical trials, locoregional failure occurs in about 8  % of patients with cervical cancer after definitive CRT with MRI-guided adaptive brachytherapy [2] and in about 6 % of patients with cervical or endometrial cancer after surgery and adjuvant RT [3,4].

Source: Radiotherapy and Oncology - April 5, 2024 Category: Radiology Authors: Fumiaki Isohashi, Ken Yoshida, Naoya Murakami, Koji Masui, Shunichi Ishihara, Yu Ohkubo, Yuko Kaneyasu, Rumiko Kinoshita, Tadayuki Kotsuma, Yuji Takaoka, Eiichi Tanaka, Ayaka Nagao, Kazuhiko Ogawa, Hideya Yamazaki Tags: Original Article Source Type: research