Alnustone promotes megakaryocyte differentiation and platelet production via the interleukin-17A/interleukin-17A receptor/Src/RAC1/MEK/ERK signaling pathway

CONCLUSIONS: Alnustone can promote megakaryocyte differentiation and platelet production via the interleukin-17A/interleukin-17A receptor/Src/RAC1/MEK/ERK signaling pathway and thus provides a new therapeutic strategy for the treatment of thrombocytopenia.PMID:38570080 | DOI:10.1016/j.ejphar.2024.176548

Source: European Journal of Pharmacology - April 3, 2024 Category: Drugs & Pharmacology Authors: Yueyue Li Jia Lai Mei Ran Taian Yi Ling Zhou Jiesi Luo Xiaoxi Liu Xiaoqin Tang Miao Huang Xiang Xie Li Hong Yan Yang Wenjun Zou Jianming Wu Source Type: research