A WNT mimetic with broad spectrum FZD-specificity decreases fibrosis and improves function in a pulmonary damage model

Wnt/ β-catenin signaling is critical for lung development and AT2 stem cell maintenance in adults, but excessive pathway activation has been associated with pulmonary fibrosis, both in animal models and human d...

Source: Respiratory Research - April 2, 2024 Category: Respiratory Medicine Authors: Mehaben Patel, Yorick Post, Natalie Hill, Asmiti Sura, Jay Ye, Trevor Fisher, Nicholas Suen, Mengrui Zhang, Leona Cheng, Ariel Pribluda, Hui Chen, Wen-Chen Yeh, Yang Li, H élène Baribault and Russell B. Fletcher Tags: Research Source Type: research