Susceptibility of Atrial Fibrillation in Genetic Architecture and Heritability: A Genome-Wide Association Study in Taiwan

Atrial fibrillation (AF) is a common arrhythmia affecting ∼34 million people worldwide1. Epidemiological studies emphasize the heritable nature of AF2. Hence, several recent studies evaluated the genetic susceptibility of AF using conventional genetic mapping approaches and genome-wide association studies (GWASs). Many common single-nucleotide polymorphi sms (SNPs) have been identified to be associated with AF3,4. However, the genetic vulnerability to AF in the Taiwanese population remains unclear.
Source: Heart Rhythm - Category: Cardiology Authors: Source Type: research