Synthesis of 3,5-disubstituted isoxazoles by domino reductive Nef reaction/cyclization of β-nitroenones

This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Muhammad Ehtisham Ibraheem Khan, Tomas Lighuen Cassini, Marino Petrini, Alessandro Palmieri β-Nitroenones can be efficently converted into 3,5-disubstituted isoxazoles by using tin(II)chloride dihydrate and ethyl acetate as reducing agent and solvent respectively. Products are obtained in good yields and several functional... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research