Disrupted gut microecology after high-dose < sup > 131 < /sup > I therapy and radioprotective effects of arachidonic acid supplementation

CONCLUSION: These findings highlight that ARA, as a key metabolite, substantially contributes to radioprotection. Our study provides novel insights into the pivotal role that the microbiota-metabolite axis plays in radionuclide protection and offers effective biological targets for treating radiation-induced adverse effects.PMID:38561516 | DOI:10.1007/s00259-024-06688-9

Source: Molecular Medicine - April 1, 2024 Category: Molecular Biology Authors: Ganghua Lu Dingwei Gao Wen Jiang Xiaqing Yu Junyu Tong Xiaoyan Liu Tingting Qiao Ru Wang Mengyu Zhang Shaoping Wang Jianshe Yang Dan Li Zhongwei Lv Source Type: research