Unveiling the vitamin E profile in rice bran extracellular vesicles: evaluation of extraction and preparation methods

This study is the first to identify tocopherol and tocotrienol in rice bran-derived EVs. Our results indicate that ultracentrifugation followed by rotation is the most effective method for the preparation of rice bran-derived EVs. Notably, the vitamin E profile in EVs varies depending on the preparation method and differs from that in rice bran extracts. The pronounced presence of vitamin E in EVs suggests unique pharmacokinetics and underscores the potential of EVs as carriers for drug delivery systems. This study not only confirms the presence of vitamin E in EVs, but also underscores the potential of EVs and their phytochemical content for therapeutic applications.PMID:38556585 | DOI:10.1007/s44211-024-00550-6
Source: Anal Sci - Category: Chemistry Authors: Source Type: research