Semi-quantitative metalloproteinase-8 rapid test for the prediction of adverse pregnancy outcomes in patients with preterm premature rupture of membranes

The preterm premature rupture of membranes (preterm PROM) complicates approximately 2  %–3% of pregnancies and precedes one-third of preterm births [1]. Although the exact aetiology remains unclear, intra-amniotic infection/inflammation is critical for preterm PROM; a causal relationship between these two has been identified [2–5]. Traditionally, the intra-amniotic infection/in flammation can be detected by conventional amniotic fluid (AF) analysis via trans-abdominal amniocentesis. Even with enough AF retrieval, microorganism cultivation may take a long time and require laboratory facilities, posing economic and human burdens.
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - Category: OBGYN Authors: Tags: Full length article Source Type: research