Radiation Dose Sensitivity of Subregions of the Larynx to Patient-Reported Swallowing Outcomes

CONCLUSIONS: These results show the relatively increased sensitivity of the epiglottis compared with the rest of the larynx when considering patient-reported decrements in quality-of-life swallowing score and support both the inclusion of the epiglottis in standard larynx contours and the assessment of the epiglottis dose during plan evaluation. Our data suggest that keeping the mean and max doses to the epiglottis <20 to 37 Gy and <53 to 60 Gy, respectively, will reduce swallowing difficulties.PMID:38550375 | PMC:PMC10973584 | DOI:10.1016/j.adro.2024.101458

Source: Adv Data - March 29, 2024 Category: Epidemiology Authors: Mark D Pepin Stephanie Anaya Yolanda I Garces Emily Hosfield Scott C Lester Daniel J Ma Daniel W Mundy Michelle A Neben-Wittich David M Routman Catherine Shonley Robert L Foote Satomi Shiraishi Source Type: research