Essential Tremor: Update of Therapeutic Strategies

Med Clin (Barc). 2024 Mar 28:S0025-7753(24)00030-7. doi: 10.1016/j.medcli.2023.12.013. Online ahead of print.ABSTRACTIn the last decades there has been progress in the treatment of essential tremor (TE) especially in the surgical field and to a lesser extent in the pharmacological field. We carry out a review of the currently available treatments. The first intervention is the use of non-pharmacological and non-surgical strategies (general advice, occupational therapy, speech therapy, psychotherapy). With discrete advances, the pharmacological treatment is not very satisfactory. Only 30-60% of patients have a positive response, and in these the anti-tremor effectiveness is 40-60%. The first-line drugs are still propranolol and primidone. In cases with severe tremor we will consider a surgical option, the method of choice being thalamotomy using high-intensity focused ultrasound. In the future we must continue to study the pathophysiology of TE, develop drugs specifically designed for TE and improve the technology of available invasive techniques.PMID:38553256 | DOI:10.1016/j.medcli.2023.12.013
Source: Medicina Clinica - Category: General Medicine Authors: Source Type: research