Chemical composition of the White Sea sponge < em > Halichondri а panicea < /em >

Nat Prod Res. 2024 Mar 28:1-8. doi: 10.1080/14786419.2024.2333049. Online ahead of print.ABSTRACTThe extract of the White Sea sponge Halichondria panicea (Pallas, 1766) exhibits cytotoxic and cytostatic effects. The main part of the extract consists of hydrophilic low molecular weight compounds: free amino acids (13.9%), glucose (19.9%), polyatomic alcohols (glycerin and others) (6.1%), carboxylic acids (0.7%) and nitrogenous heterocycles (1.2%). Of the substances specific to the metabolome, bicyclic diketopiperazines (four derivatives), pyroglutamic acid, phenylacetic acid, and two steroids (3β,5α)cholest-7-en-3-ol and dihydrocholesterol were identified. Toxicants characteristic of the genus Halichondria were not found in the White Sea sponge.PMID:38547385 | DOI:10.1080/14786419.2024.2333049

Source: Natural Product Research - March 28, 2024 Category: Biochemistry Authors: Konstantin A Krasnov Alexander Yu Gorbunov Nadezhda Yu Rogovskaja Viktor A Utsal Vladimir T Papp Alexandra A Krasnova Semen S Gaft Vyacheslav V Khalaman Source Type: research