Grey-to-white matter ratio values in early head CT as a predictor of neurological outcomes in survivors of out-of-hospital cardiac arrest based on severity of hypoxic-ischemic brain injury

Out-of-hospital cardiac arrest (OHCA) is a global public health challenge experienced by approximately 3.8 million people annually, with only 8 –12% surviving to hospital discharge, imposing a considerable socioeconomic burden1,2. Hypoxic-ischemic brain injury (HIBI) is the most frequent cardiac arrest complication, resulting in poor neurological outcomes and low survival rates in OHCA survivors3-6. Only 10% of people who experience OHCA can expect to survive with a good neurological outcome1. The international guidelines for post-cardiac arrest syndrome care recommend that prognostic predictions be made after 72 h of the return of spontaneous circulation (ROSC) to prevent inappropriate withdrawal of life-sustaining therapy; therefo re, early prediction of neurological outcomes in patients with post-cardiac arrest syndrome is essential for planning treatment and determining the appropriate withdrawal of life-sustaining therapy7.
Source: The Journal of Emergency Medicine - Category: Emergency Medicine Authors: Tags: Selected Topics: Prehospital Care Source Type: research