In-silico Studies, Synthesis, and Antacid Activities of Magnesium (II) Complexes

CONCLUSION: The antacid activities of Mg (II) complexes were excellent as compared to the semicarbazone ligand and comparable with that of marketed antacid drugs like ENO, and Pantop-D. Insilco studies also confirmed that semicarbazone ligand and its Mg (II) complexes were both found to be fitted into the active sites of molecular targets, and Mg (II) complexes showed better binding affinities towards macromolecular as compared to semicarbazone ligand.PMID:38509676 | DOI:10.2174/0115701638276401240315084143
Source: Current Drug Discovery Technologies - Category: Drugs & Pharmacology Authors: Source Type: research